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KMID : 0363420120260040061
Journal of Korean Oriental Pediatrics
2012 Volume.26 No. 4 p.61 ~ p.70
The Literature Study on Treatment of Down¡¯s Syndrome - Within Chinese Medical Journal -
Jung Jun-Suk

Kim Ki-Bong
Abstract
Objectives: Literature Study of clinical cases with Traditional Chinese Medicine (TCM) as reference for Korean medicine based treatment of juvenile patients with Down¡¯s syndrome.

Methods: 4 TCM journals with the highest impact factors were searched and selected among the journals listed in www.cnki.net. The search keywords were "ÙÕͯñø", "ÓÐä«ñø(ߧßæÓÐä«ñø)", "ÓÐä«ñøý¦ÏØ", "à»ô¸é×úþ", "ãßàßåÆöÁ?", "21ß²?ðüùêó£", "ß²æøßä?ñø", "Down¡¯s syndrome", and "Mongolism". Accordingly, searched papers were analyzed.

Results: Total 6 studies were selected: RCT(5), case report(1). Among the RCT related studies, 2 studies tested the effect of Electroacupuncture (ï³öÝ), 1 study tested the effect of Electroacupuncture and Pharmacopuncture (å·öÝ) treatment together, and 2 studies tested the effect of Electroacupuncture and Herbal Medicines (å·Úª) co-treatment. In all the studies, the study groups showed significantly improved intelligence quotient (IQ) in comparison with the control groups. The case report showed improvement of cognitive ability and other clinical parameters as a result of Acupuncture (öÝ) and Herbal Medicines co-treatment in juvenile patients with Down¡¯s syndrome.

Conclusions: Clinical studies testing the effect of TCM for the treatment of Down¡¯s syndrome have been conducted in small scales, and all the studies showed a certain level of brain function improvement of the patients in the study groups. These results implicate that the methods in Korean medicine can be highly potential treatment options for the treatment of Down¡¯s syndrome. Conduction of accurate and well-controlled studies in large scale would be required to prove the effect of Korean medicine for the treatment of patients with Down¡¯s syndrome.
KEYWORD
Down¡¯s syndrome, Mongolism, Acupuncture, Herbal Medicines, Randomized Controlled Trial, Review
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